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Thursday, September 2
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Flavins and oxygen Hydroxylases, Monooxygenases |
Chair: Ballou
Speakers: |
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08.45 | Coenzyme recognition by flavoprotein aromatic hydroxylases |
van Berkel (30 min.)
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09.15 | Wavin' flavins and passwords: dynamics and control in the reactions of p-hydroxybenzoate hydroxylase |
Palfey (30 min.)
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09.45 | Hydroxylation by flavin enzymes: evidence for NIH-shift mechanism |
Eisenreich (30 min.)
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10.15 | Coffee break | |
Flavoproteins and "C-H-substrates", mechanisms |
Chair: Lederer
Speakers: |
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10.45 | Structural biology of oxidases: L-aspartate oxidase, vanillyl-alcohol oxidase and polyamine oxidase |
Fraaije (30 min.)
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11.15 | DAAO structure and mechanisms |
Miura (30 min.)
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11.45 | DAAO mechanisms |
Pollegioni (30 min.)
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12.15 | Biochemical and structural characterization of monomeric sarcosine oxidase a D-amino acid oxidase/monoamine oxidase hybrid |
Jorns (30 min.)
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12.45 | Acyl-CoA dehydrogenases, evolution of an active site |
Kim (30 min.)
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13.15 - 14.30 |
Lunch | |
15.00 - 18.00 |
Poster session (P01 - X05) & Coffee break | |
18.30 - 19.30 |
Dinner | |
19.45 - 20.35 |
Evening Lecture: Dihydrolipoyl dehydrogenase, the complex flavoprotein |
Chair: Scrutton
Speaker: Perham (50 min.) |
20.35 - 20.55 |
Structure and function of the flavin reductase FRase I from the bioluminescent bacterium Vibrio fischeri: X-ray crystallography of FRase I mutants and complexes with inhibitors |
Tanokura (20 min.)
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20.55 - 21.45 |
Poster discussion and short talks on the topics of the day. |
Barna (10 min.)
Mewies (10 min.) Schaller (10 min.) Strassner (10 min.) |
21.45 - 22.05 |
Computer visualisation of flavin-dependent aromatic hydroxylation |
Ridder (20 min)
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